If cooking thawed chicken breasts you should figure about 8 to 10 minutes. When using frozen chicken breasts you will want to set your instapot for 10 to 12 minutes. Be sure to put 1/2 cup to 1 cup of liquid into the pot, then place your seasoned chicken on top of the trivet. Set your instapot for the desired time and then let it natural release for 6 minutes.